Palliation of metastatic bone pain: single fraction versus multifraction radiotherapy
نویسندگان
چکیده
منابع مشابه
Palliation of metastatic bone pain: single fraction versus multifraction radiotherapy - a systematic review of the randomised trials.
BACKGROUND Recent randomised studies reported that single fraction radiotherapy was as effective as multifraction radiotherapy in relieving pain due to bone metastasis. However, there are concerns about the higher re-treatment rates and the efficacy of preventing future complications such as pathological fracture and spinal cord compression by single fraction radiotherapy. OBJECTIVES To under...
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External beam radiotherapy (EBRT) is an effective treatment for symptomatic bone metastases from a variety of primary malignancies. Previous meta-analyses and systematic reviews have reported on the efficacy of EBRT on bone metastases from multiple primaries. This review is focused on the comparative effectiveness of single fraction radiotherapy versus multiple fraction radiotherapy for bone me...
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BACKGROUND The Radiation Therapy Oncology Group (RTOG) trial 97-14 revealed no difference between radiation delivered for painful bone metastases at a dose of 8 gray (Gy) in 1 fraction (single-fraction radiotherapy [SFRT]) and 30 Gy in 10 fractions (multifraction radiotherapy [MFRT]) in pain relief or narcotic use 3 months after randomization. SFRT for painful vertebral bone metastases (PVBM) h...
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Metastatic bone disease is a commonly encountered problem in oncology practice. Many patients with cancer, though heavily treated, ultimately metastasise. One of the important sites of metastasis is bone. Bone metastases can cause severe and debilitating effects, including pain, pathological fracture, hypercalcaemia and spinal cord compression. [1] Palliative external beam radiotherapy (EBRT) i...
متن کاملRe: Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases.
The role of radiotherapy in the palliation of painful symptomatic bone metastases is well established. Recently, it has been reported that single-fraction radiotherapy is as effective as multifraction radiotherapy ( 1 , 2 ) , which is the most widely used regimen. We read the interest the article by Hartsell et al. ( 3 ) , which compared the ability of a single 8-Gy fraction of radiation therap...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2002
ISSN: 1465-1858
DOI: 10.1002/14651858.cd004721